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My research is focused on components of self-control and risk taking. I am interested in mechanisms of impulsivity and in how these overlapping and dimensional features of psychopathology help us understand the etiology and boundaries of specific disorders. In one line of research, I investigate the heritability and genetic underpinnings of these traits, their prevalence and relationships across genetically related disorders, and their associations with negative outcomes such as suicide and pathological gambling. In another, I am particularly focused on the self-control required to initiate and maintain effortful activity in the absence of short-term reward, and on the mechanisms of effort conservation and regulation in schizophrenia.